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Semax Research Guide: Neuroprotection, Cognitive Enhancement & CNS Studies (2026)

Research Use Only. Semax is a research peptide intended strictly for laboratory and scientific use. Not for human consumption or therapeutic application.

What is Semax?

Semax is a synthetic heptapeptide based on the ACTH(4-7) fragment — Met-Glu-His-Phe-Pro-Gly-Pro. Developed in Russia, it has been studied for its potential effects on neuroprotection, cognitive enhancement, BDNF regulation, and central nervous system recovery in preclinical models.

Semax in Preclinical Research

  • BDNF upregulation — Preclinical studies have shown Semax significantly increases brain-derived neurotrophic factor (BDNF) and its receptor TrkB expression in rat hippocampal models.
  • Neuroprotection — Research in ischemia models has explored Semax’s potential to reduce neuronal damage and support brain recovery following oxygen deprivation.
  • Cognitive function — Animal studies have examined Semax’s effects on memory formation, learning capacity, and attention in maze and behavioral research models.
  • Dopamine system modulation — Research has explored Semax’s interaction with dopaminergic pathways and its potential effects on motivation and reward circuitry.
  • Anti-inflammatory CNS effects — Studies have investigated Semax’s role in modulating neuroinflammatory markers in CNS injury models.

Molecular Profile

  • Sequence: Met-Glu-His-Phe-Pro-Gly-Pro
  • Molecular Formula: C₃₇H₅₁N₉O₁₀S
  • Molecular Weight: 813.92 g/mol
  • Form: Lyophilized powder
  • Purity: 99% (HPLC verified)
  • Storage: -20°C, away from light and moisture

Sourcing Semax for Research

Shop Semax 10mg at Peppy University with 99% purity, HPLC verified, and full research documentation.

All products at Peppy University are intended strictly for laboratory and scientific research purposes only. Not for human consumption. Research Use Only.

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