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Category: Cognitive Function

Research on cognitive and nootropic peptides

  • Dihexa Research Guide: Cognitive Enhancement, Neurogenesis & Memory Studies (2026)

    Research Use Only. Dihexa is a research compound intended strictly for laboratory and scientific use. Not for human consumption or therapeutic application.

    What is Dihexa?

    Dihexa (N-hexanoic-Tyr-Ile-(6) aminohexanoic amide) is a small peptide derived from Angiotensin IV, developed by researchers at Washington State University. It has been studied in preclinical research for its remarkable potency in cognitive enhancement, synaptogenesis, and neurological repair models — reported to be millions of times more potent than BDNF in certain hippocampal synaptogenesis assays.

    Dihexa in Preclinical Research

    • Synaptogenesis — Preclinical data demonstrates Dihexa’s ability to promote new synapse formation through hepatocyte growth factor (HGF) and its receptor c-Met, critical pathways in learning and memory research.
    • Cognitive function in aging models — Research in rodent models of cognitive decline has shown significant improvements in spatial memory and learning tasks following Dihexa administration.
    • Neurological repair — Studies have explored Dihexa’s potential in neurodegenerative disease models, examining its effects on neuronal survival and plasticity.
    • HGF/c-Met pathway — Dihexa’s primary mechanism involves potentiating HGF activity, which regulates neuronal growth, survival, and differentiation.

    Molecular Profile

    • Molecular Formula: C₂₄H₃₉N₃O₄
    • Molecular Weight: 437.58 g/mol
    • Form: Lyophilized powder
    • Purity: 99% (HPLC verified)
    • Storage: -20°C, dry and dark conditions

    Sourcing Dihexa for Research

    Shop Dihexa 10mg at Peppy University — one of the most studied nootropic peptides in preclinical research, supplied at 99% purity with full HPLC documentation.

    All products at Peppy University are intended strictly for laboratory and scientific research purposes only. Not for human consumption. Research Use Only.

  • Semax Research Guide: Neuroprotection, Cognitive Enhancement & CNS Studies (2026)

    Research Use Only. Semax is a research peptide intended strictly for laboratory and scientific use. Not for human consumption or therapeutic application.

    What is Semax?

    Semax is a synthetic heptapeptide based on the ACTH(4-7) fragment — Met-Glu-His-Phe-Pro-Gly-Pro. Developed in Russia, it has been studied for its potential effects on neuroprotection, cognitive enhancement, BDNF regulation, and central nervous system recovery in preclinical models.

    Semax in Preclinical Research

    • BDNF upregulation — Preclinical studies have shown Semax significantly increases brain-derived neurotrophic factor (BDNF) and its receptor TrkB expression in rat hippocampal models.
    • Neuroprotection — Research in ischemia models has explored Semax’s potential to reduce neuronal damage and support brain recovery following oxygen deprivation.
    • Cognitive function — Animal studies have examined Semax’s effects on memory formation, learning capacity, and attention in maze and behavioral research models.
    • Dopamine system modulation — Research has explored Semax’s interaction with dopaminergic pathways and its potential effects on motivation and reward circuitry.
    • Anti-inflammatory CNS effects — Studies have investigated Semax’s role in modulating neuroinflammatory markers in CNS injury models.

    Molecular Profile

    • Sequence: Met-Glu-His-Phe-Pro-Gly-Pro
    • Molecular Formula: C₃₇H₅₁N₉O₁₀S
    • Molecular Weight: 813.92 g/mol
    • Form: Lyophilized powder
    • Purity: 99% (HPLC verified)
    • Storage: -20°C, away from light and moisture

    Sourcing Semax for Research

    Shop Semax 10mg at Peppy University with 99% purity, HPLC verified, and full research documentation.

    All products at Peppy University are intended strictly for laboratory and scientific research purposes only. Not for human consumption. Research Use Only.

  • Selank Research Guide: Anxiolytic Pathways, Cognitive Function & Nootropic Studies (2026)

    Research Use Only. Selank is a research peptide intended strictly for laboratory and scientific use. Not for human consumption or therapeutic application.

    What is Selank?

    Selank is a synthetic heptapeptide analog of the human tetrapeptide tuftsin (Thr-Lys-Pro-Arg), developed by the Institute of Molecular Genetics of the Russian Academy of Sciences. In preclinical research, Selank has been studied for its potential effects on anxiety pathways, cognitive function, immune modulation, and neuroprotection.

    Selank in Preclinical Research

    • Anxiolytic pathways — Selank has been studied in animal models for its interaction with GABA-A receptor systems and its potential anxiolytic effects without sedative properties.
    • Cognitive enhancement — Research has explored Selank’s effects on brain-derived neurotrophic factor (BDNF) expression and memory consolidation pathways in rodent models.
    • Immune modulation — As a tuftsin analog, Selank has been studied for its effects on T-cell activity, NK cell function, and cytokine regulation.
    • Enkephalin metabolism — Preclinical data suggests Selank may inhibit enkephalin-degrading enzymes, potentially modulating endogenous opioid signaling pathways.
    • Stress response — Studies have examined Selank’s effects on HPA axis activity and corticosterone levels in stress model research.

    Molecular Profile

    • Sequence: Thr-Lys-Pro-Arg-Pro-Gly-Pro
    • Molecular Formula: C₃₃H₅₇N₁₁O₉
    • Molecular Weight: 751.87 g/mol
    • Form: Lyophilized powder
    • Purity: 99% (HPLC verified)
    • Storage: -20°C, dark, dry conditions

    Sourcing Selank for Research

    Shop Selank 10mg at Peppy University — third-party tested, 99% purity with full documentation for laboratory research use.

    All products at Peppy University are intended strictly for laboratory and scientific research purposes only. Not for human consumption. Research Use Only.